Kessler RC, Berglund P, Demler O, Jin R, Koretz D, Merikangas KR. The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). JAMA. 2003;289:3095-105.

Prince M, Patel V, Saxena S, Maj M, Maselko J, Phillips MR. No health without mental health. Lancet. 2007;370:859-77.

Saarni SI, Suvisaari J, Sintonen H, Pirkola S, Koskinen S, Aromaa A. Impact of psychiatric disorders on health-related quality of life: general population survey. Br J Psychiatry. 2007;190:326-32.

Ustun TB, Ayuso-Mateos JL, Chatterji S, Mathers C, Murray CJ. Global burden of depressive disorders in the year 2000. Br J Psychiatry. 2004;184:386-92.

Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med. 2006;3:e442.

Blanchard RJ, McKittrick CR, Blanchard DC. Animal models of social stress: effects on behavior and brain neurochemical systems. Physiol Behav. 2001;73:261-71.

Sapolsky RM. The influence of social hierarchy on primate health. Science. 2005;308:648-52.

Von Holst D. The concept of stress and its relevance for animal behavior.. Adv Study Behav USA [Internet]. 1998.

Raab A, Dantzer R, Michaud B, Mormede P, Taghzouti K, Simon H. Behavioural, physiological and immunological consequences of social status and aggression in chronically coexisting resident-intruder dyads of male rats. Physiol Behav. 1986;36:223-8.

Koolhaas JM, Schuurman T, Wiepkema PR. The organization of intraspecific agonistic behaviour in the rat. Prog Neurobiol. 1980;15:247-68.

Miczek KA. A new test for aggression in rats without aversive stimulation: differential effects of d-amphetamine and cocaine. Psychopharmacology (Berl). 1979;60:253-9.

Albonetti ME, Farabollini F. Social stress by repeated defeat: effects on social behaviour and emotionality. Behav Brain Res. 1994;62:187-93.

Fuchs E, Flügge G. Social stress in tree shrews: effects on physiology, brain function, and behavior of subordinate individuals. Pharmacol Biochem Behav. 2002;73:247-58.

Keeney AJ, Hogg S, Marsden CA. Alterations in core body temperature, locomotor activity, and corticosterone following acute and repeated social defeat of male NMRI mice. Physiol Behav. 2001;74:177-84.

Marini F, Pozzato C, Andreetta V, Jansson B, Arban R, Domenici E. Single exposure to social defeat increases corticotropin-releasing factor and glucocorticoid receptor mRNA expression in rat hippocampus. Brain Res. 2006;1067:25-35.

Sapolsky RM. Why zebras don't get ulcers. 2004.

McEwen BS. Central effects of stress hormones in health and disease: Understanding the protective and damaging effects of stress and stress mediators. Eur J Pharmacol. 2008;583:174-85.

Chen P, Fan Y, Li Y, Sun Z, Bissette G, Zhu MY. Chronic social defeat up-regulates expression of norepinephrine transporter in rat brains. Neurochem Int. 2012;60:9-20.

De Kloet ER, Vreugdenhil E, Oitzl MS, Joëls M. Brain corticosteroid receptor balance in health and disease. Endocr Rev. 1998;19:269-301.

Kovács KJ, Földes A, Sawchenko PE. Glucocorticoid negative feedback selectively targets vasopressin transcription in parvocellular neurosecretory neurons. J Neurosci. 2000;20:3843-52.

Pace TW, Spencer RL. Disruption of mineralocorticoid receptor function increases corticosterone responding to a mild, but not moderate, psychological stressor. Am J Physiol Endocrinol Metab. 2005;288:E1082-8.

Bartolomucci A, Palanza P, Costoli T, Savani E, Laviola G, Parmigiani S. Chronic psychosocial stress persistently alters autonomic function and physical activity in mice. Physiol Behav. 2003;80:57-67.

Razzoli M, Carboni L, Guidi A, Gerrard P, Arban R. Social defeat-induced contextual conditioning differentially imprints behavioral and adrenal reactivity: a time-course study in the rat. Physiol Behav. 2007;92:734-40.

Bartolomucci A, Palanza P, Gaspani L, Limiroli E, Panerai AE, Ceresini G. Social status in mice: behavioral, endocrine and immune changes are context dependent. Physiol Behav. 2001;73:401-10.

Meerlo P, Overkamp GJ, Daan S, Van Den Hoofdakker RH, Koolhaas JM. Changes in behaviour and body weight following a single or double social defeat in rats. Stress. 1996;1:21-32.

Padgett DA, Glaser R. How stress influences the immune response. Trends Immunol. 2003;24:444-8.

Sgoifo A, Costoli T, Meerlo P, Buwalda B, Pico'-Alfonso MA, De Boer S. Individual differences in cardiovascular response to social challenge. Neurosci Biobehav Rev. 2005;29:59-66.

Miczek KA, Yap JJ, Covington 3rd HE. Social stress, therapeutics and drug abuse: preclinical models of escalated and depressed intake. Pharmacol Ther. 2008;120:102-28.

Badiani A, Rajabi H, Nencini P, Stewart J. Modulation of food intake by the ? opioid U-50,488H: evidence for an effect on satiation. Behav Brain Res. 2001;118:179-86.

Vanderschuren LJ, Kalivas PW. Alterations in dopaminergic and glutamatergic transmission in the induction and expression of behavioral sensitization: a critical review of preclinical studies. Psychopharmacology (Berl). 2000;151:99-120.

Covington 3rd HE, Miczek KA. Repeated social-defeat stress, cocaine or morphine. Effects on behavioral sensitization and intravenous cocaine self-administration "binges". Psychopharmacology (Berl). 2001;158:388-98.

Nikulina EM, Covington 3rd HE, Ganschow L, Hammer Jr RP, Miczek KA. Long-term behavioral and neuronal cross-sensitization to amphetamine induced by repeated brief social defeat stress: Fos in the ventral tegmental area and amygdala. Neuroscience. 2004;123:857-65.

Robinson TE, Berridge KC. The psychology and neurobiology of addiction: an incentive-sensitization view. Addiction. 2000;95:S91-117.

Tidey JW, Miczek KA. Social defeat stress selectively alters mesocorticolimbic dopamine release: an in vivo microdialysis study. Brain Res. 1996;721:140-9.

Yerkes RM, Dodson JD. The relation of strength of stimulus to rapidity of habit-formation. J Comp Neurol Psychol. 1908;18:459-82.

Diamond DM, Campbell AM, Park CR, Halonen J, Zoladz PR. The temporal dynamics model of emotional memory processing: a synthesis on the neurobiological basis of stress-induced amnesia, flashbulb and traumatic memories, and the Yerkes-Dodson law. Neural Plast. 2007;2007:60803.

Miczek KA, Nikulina EM, Shimamoto A, Covington 3rd HE. Escalated or suppressed cocaine reward, tegmental BDNF and accumbal dopamine due to episodic vs: continuous social stress in rats. J Neurosci. 2011;31:9848-57.

Wang J, Fanous S, Terwilliger EF, Bass CE, Hammer Jr RP, Nikulina EM. BDNF overexpression in the ventral tegmental area prolongs social defeat stress-induced cross-sensitization to amphetamine and increases?FosB expression in mesocorticolimbic regions of rats. Neuropsychopharmacology. 2013;38:2286-96.

Nikulina EM, Lacagnina MJ, Fanous S, Wang J, Hammer Jr RP. Intermittent social defeat stress enhances mesocorticolimbic? FosB/BDNF co-expression and persistently activates corticotegmental neurons: implication for vulnerability to psychostimulants. Neuroscience. 2012;212:38-48.

Koolhaas JM, Meerlo P, de Boer SF, Strubbe JH, Bohus B. The temporal dynamics of the stress response. Neurosci Biobehav Rev. 1997;21:775-82.

Rygula R, Abumaria N, Domenici E, Hiemke C, Fuchs E. Effects of fluoxetine on behavioral deficits evoked by chronic social stress in rats. Behav Brain Res. 2006;174:188-92.

Von Frijtag JC, Kamal A, Reijmers LG, Schrama LH, van den Bos R, Spruijt BM. Chronic imipramine treatment partially reverses the long-term changes of hippocampal synaptic plasticity in socially stressed rats. Neurosci Lett. 2001;309:153-6.

Kendler KS, Karkowski-Shuman L. Stressful life events and genetic liability to major depression: genetic control of exposure to the environment?. Psychol Med. 1997;27:539-47.

Koolhaas JM, de Boer SF, Buwalda B, van Reenen K. Individual variation in coping with stress: a multidimensional approach of ultimate and proximate mechanisms. Brain Behav Evol. 2007;70:218-26.

Pawlak CR, Ho YJ, Schwarting RK. Animal models of human psychopathology based on individual differences in novelty-seeking and anxiety. Neurosci Biobehav Rev. 2008;32:1544-68.

Duclot F, Kabbaj M. Individual differences in novelty seeking predict subsequent vulnerability to social defeat through a differential epigenetic regulation of brain-derived neurotrophic factor expression. J Neurosci. 2013;33:11048-60.

Harro J. Inter-individual differences in neurobiology as vulnerability factors for affective disorders: Implications for psychopharmacology. Pharmacol Ther. 2010;125:402.

Hollis F, Duclot F, Gunjan A, Kabbaj M. Individual differences in the effect of social defeat on anhedonia and histone acetylation in the rat hippocampus. Horm Behav. 2011;59:331-7.

Piazza PV, Deminière JM, Le Moal M, Simon H. Factors that predict individual vulnerability to amphetamine self-administration. Science. 1989;245:1511-3.

Duclot F, Hollis F, Darcy MJ, Kabbaj M. Individual differences in novelty-seeking behavior in rats as a model for psychosocial stress-related mood disorders. Physiol Behav. 2011;104:296-305.

Razzoli M, Carboni L, Arban R. Alterations of behavioral and endocrinological reactivity induced by 3 brief social defeats in rats: relevance to human psychopathology. Psychoneuroendocrinology. 2009;34:1405-16.

Bourke CH, Raees MQ, Malviya S, Bradburn CA, Binder EB, Neigh GN. Glucocorticoid sensitizers Bag1 and Ppid are regulated by adolescent stress in a sex-dependent manner. Psychoneuroendocrinology. 2013;38:84-93.

Green MK, Rani CS, Joshi A, Soto-Piña AE, Martinez PA, Frazer A. Prenatal stress induces long term stress vulnerability, compromising stress response systems in the brain and impairing extinction of conditioned fear after adult stress. Neuroscience. 2011;192:438-51.

Kamal A, Van der Harst JE, Kapteijn CM, Baars AJ, Spruijt BM, Ramakers GM. Announced reward counteracts the effects of chronic social stress on anticipatory behavior and hippocampal synaptic plasticity in rats. Exp Brain Res. 2010;201:641-51.

Burgdorf J, Kroes RA, Beinfeld MC, Panksepp J, Moskal JR. Uncovering the molecular basis of positive affect using rough-and-tumble play in rats: a role for insulin-like growth factor I. Neuroscience. 2010;168:769-77.

Fekete ÉM, Zhao Y, Li C, Sabino V, Vale WW, Zorrilla EP. Social defeat stress activates medial amygdala cells that express type 2 corticotropin-releasing factor receptor mRNA. Neuroscience. 2009;162:5-13.

Funk D, Li Z, Lê AD. Effects of environmental and pharmacological stressors on c-fos and corticotropin-releasing factor mRNA in rat brain: Relationship to the reinstatement of alcohol seeking. Neuroscience. 2006;138:235-43.

Gardner KL, Thrivikraman KV, Lightman SL, Plotsky PM, Lowry CA. Early life experience alters behavior during social defeat: focus on serotonergic systems. Neuroscience. 2005;136:181-91.

Gardner KL, Hale MW, Oldfield S, Lightman SL, Plotsky PM, Lowry CA. Adverse experience during early life and adulthood interact to elevate tph2 mRNA expression in serotonergic neurons within the dorsal raphe nucleus. Neuroscience. 2009;163:991-1001.

Gardner KL, Hale MW, Lightman SL, Plotsky PM, Lowry CA. Adverse early life experience and social stress during adulthood interact to increase serotonin transporter mRNA expression. Brain Res. 2009;1305:47-63.

Green MK, Devine DP. Nociceptin/orphanin FQ and NOP receptor gene regulation after acute or repeated social defeat stress. Neuropeptides. 2009;43:507-14.

Kavushansky A, Ben-Shachar D, Richter-Levin G, Klein E. Physical stress differs from psychosocial stress in the pattern and time-course of behavioral responses, serum corticosterone and expression of plasticity-related genes in the rat. Stress. 2009;12:412-25.

Paul ED, Hale MW, Lukkes JL, Valentine MJ, Sarchet DM, Lowry CA. Repeated social defeat increases reactive emotional coping behavior and alters functional responses in serotonergic neurons in the rat dorsal raphe nucleus. Physiol Behav. 2011;104:272-82.

Carboni L, Piubelli C, Pozzato C, Astner H, Arban R, Righetti PG. Proteomic analysis of rat hippocampus after repeated psychosocial stress. Neuroscience. 2006;137:1237-46.

Olivares EL, Silva-Almeida C, Pestana FM, Sonoda-Côrtes R, Araujo IG, Rodrigues NC. Social stress-induced hypothyroidism is attenuated by antidepressant treatment in rats. Neuropharmacology. 2012;62:446-56.

Furay AR, McDevitt RA, Miczek KA, Neumaier JF. 5-HT1B mRNA expression after chronic social stress. Behav Brain Res. 2011;224:350-7.

Turner CA, Calvo N, Frost DO, Akil H, Watson SJ. The fibroblast growth factor system is downregulated following social defeat. Neurosci Lett. 2008;430:147-50.

Hueston CM, Barnum CJ, Eberle JA, Ferraioli FJ, Buck HM, Deak T. Stress-dependent changes in neuroinflammatory markers observed after common laboratory stressors are not seen following acute social defeat of the Sprague Dawley rat. Physiol Behav. 2011;104:187-98.

Kabbaj M, Evans S, Watson SJ, Akil H. The search for the neurobiological basis of vulnerability to drug abuse: using microarrays to investigate the role of stress and individual differences. Neuropharmacology. 2004;47:111-22.

Kroes RA, Burgdorf J, Otto NJ, Panksepp J, Moskal JR. Social defeat, a paradigm of depression in rats that elicits 22-khz vocalizations, preferentially activates the cholinergic signaling pathway in the periaqueductal gray. Behav Brain Res. 2007;182:290-300.

Niikura S, Yokoyama O, Komatsu K, Yotsuyanagi S, Mizuno T, Namiki M. A causative factor of copulatory disorder in rats following social stress. J Urol. 2002;168:843-9.

Burke AR, Watt MJ, Forster GL. Adolescent social defeat increases adult amphetamine conditioned place preference and alters D2 dopamine receptor expression. Neuroscience. 2011;197:269-79.

Buwalda B, Stubbendorff C, Zickert N, Koolhaas JM. Adolescent social stress does not necessarily lead to a compromised adaptive capacity during adulthood: a study on the consequences of social stress in rats. Neuroscience. 2013;249:258-70.

Nocjar C, Zhang J, Feng P, Panksepp J. The social defeat animal model of depression shows diminished levels of orexin in mesocortical regions of the dopamine system, and of dynorphin and orexin in the hypothalamus. Neuroscience. 2012;218:138-53.

Covington 3rd HE, Miczek KA. Intense cocaine self-administration after episodic social defeat stress, but not after aggressive behavior: dissociation from corticosterone activation. Psychopharmacology (Berl). 2005;183:331-40.

Fanous S, Hammer Jr RP, Nikulina EM. Short- and long-term effects of intermittent social defeat stress on brain-derived neurotrophic factor expression in mesocorticolimbic brain regions. Neuroscience. 2010;167:598-607.

Fanous S, Terwilliger EF, Hammer Jr RP, Nikulina EM. Viral depletion of VTA BDNF in rats modulates social behavior, consequences of intermittent social defeat stress, and long-term weight regulation. Neurosci Lett. 2011;502:192-6.

Grunewald M, Johnson S, Lu D, Wang Z, Lomberk G, Albert PR. Mechanistic role for a novel glucocorticoid-klf11 (tieg2) protein pathway in stress-induced monoamine oxidase a expression. J Biol Chem. 2012;287:24195-206.

Iio W, Matsukawa N, Tsukahara T, Kohari D, Toyoda A. Effects of chronic social defeat stress on MAP kinase cascade. Neurosci Lett. 2011;504:281-4.

Kanarik M, Alttoa A, Matrov D, Kõiv K, Sharp T, Panksepp J. Brain responses to chronic social defeat stress: effects on regional oxidative metabolism as a function of a hedonic trait, and gene expression in susceptible and resilient rats. Eur Neuropsychopharmacol. 2011;21:92-107.

Ordway GA, Szebeni A, Chandley MJ, Stockmeier CA, Xiang L, Newton SS. Low gene expression of bone morphogenetic protein 7 in brainstem astrocytes in major depression. Int J Neuropsychopharmacol. 2012;15:855-68.

Kieran N, Ou XM, Iyo AH. Chronic social defeat downregulates the 5-HT1A receptor but not Freud-1 or NUDR in the rat prefrontal cortex. Neurosci Lett. 2010;469:380-4.

Tornatzky W, Miczek KA. Long-term impairment of autonomic circadian rhythms after brief intermittent social stress. Physiol Behav. 1993;53:983-93.

Tornatzky W, Miczek KA. Behavioral and autonomic responses to intermittent social stress: differential protection by clonidine and metoprolol. Psychopharmacology (Berl). 1994;116:346-56.

Marini F, Pozzato C, Andreetta V, Jansson B, Arban R, Domenici E. Single exposure to social defeat increases corticotropin-releasing factor and glucocorticoid receptor mRNA expression in rat hippocampus. Brain Res. 2006;1067:25-35.

Potter E, Sutton S, Donaldson C, Chen R, Perrin M, Lewis K. Distribution of corticotropin-releasing factor receptor mRNA expression in the rat brain and pituitary. Proc Natl Acad Sci U S A. 1994;91:8777-81.

Zorrilla EP, Koob GF. The therapeutic potential of CRF1 antagonists for anxiety. Expert Opin Investig Drugs. 2004;13:799-828.

Luiten PGM, Koolhaas JM, de Boer S, Koopmans SJ. The cortico-medial amygdala in the central nervous system organization of agonistic behavior. Brain Res. 1985;332:283-97.

Blanchard DC, Canteras NS, Markham CM, Pentkowski NS, Blanchard RJ. Lesions of structures showing FOS expression to cat presentation: Effects on responsivity to a Cat, Cat odor, and nonpredator threat. Neurosci Biobehav Rev. 2005;29:1243-53.

Dayas CV, Buller KM, Day TA. Neuroendocrine responses to an emotional stressor: evidence for involvement of the medial but not the central amygdala. Eur J Neurosci. 1999;11:2312-22.

Blandino Jr P, Barnum CJ, Solomon LG, Larish Y, Lankow BS, Deak T. Gene expression changes in the hypothalamus provide evidence for regionally-selective changes in IL-1 and microglial markers after acute stress. Brain Behav Immun. 2009;23:958-68.

Johnson JD, Campisi J, Sharkey CM, Kennedy SL, Nickerson M, Greenwood BN. Catecholamines mediate stress-induced increases in peripheral and central inflammatory cytokines. Neuroscience. 2005;135:1295-307.

O'Connor KA, Johnson JD, Hansen MK, Wieseler Frank JL, Maksimova E, Watkins LR. Peripheral and central proinflammatory cytokine response to a severe acute stressor. Brain Res. 2003;991:123-32.

Covington 3rd HE, Kikusui T, Goodhue J, Nikulina EM, Hammer Jr RP, Miczek KA. Brief social defeat stress: long lasting effects on cocaine taking during a binge and zif268 mRNA expression in the amygdala and prefrontal cortex. Neuropsychopharmacology. 2005;30:310-21.

Nestler EJ, Kelz MB. Brain. Res. 1999;835:10-7.

Geisler S, Zahm DS. Afferents of the ventral tegmental area in the rat-anatomical substratum for integrative functions. J Comp Neurol. 2005;490:270-94.

Kalivas PW, Duffy P, Latimer LG. Neurochemical and behavioral effects of corticotropin-releasing factor in the ventral tegmental area of the rat. J Pharmacol Exp Ther. 1987;242:757-63.

Fanselow MS, Dong HW. Are the dorsal and ventral hippocampus functionally distinct structures. Neuron. 2010;65:7-19.

Castagné V, Moser P, Roux S, Porsolt RD. Rodent models of depression: forced swim and tail suspension behavioral despair tests in rats and mice. Current Protocols in Neuroscience. 2011.

Chang L, Karin M. Mammalian MAP kinase signalling cascades. Nature. 2001;410:37-40.

Muschamp JW, Dominguez JM, Sato SM, Shen RY, Hull EM. A role for hypocretin (orexin) in male sexual behavior. J Neurosci. 2007;27:2837-45.

Nestler EJ, Carlezon Jr WA. The mesolimbic dopamine reward circuit in depression. Biol Psychiatry. 2006;59:1151-9.

Brain P, Benton D. The interpretation of physiological correlates of differential housing in laboratory rats. Life Sci. 1979;24:99-115.

McEwen BS. Allostasis and allostatic load: implications for neuropsychopharmacology. Neuropsychopharmacology. 2000;22:108-24.

Sánchez C. Stress-induced vocalisation in adult animals. A valid model of anxiety?. Eur J Pharmacol. 2003;463:133-43.

Miczek KA, Weerts EM, Vivian JA, Barros HM. Aggression, anxiety and vocalizations in animals: GABAA and 5-HT anxiolytics. Psychopharmacology (Berl). 1995;121:38-56.

Montgomery SA, Baldwin DS, Blier P, Fineberg NA, Kasper S, Lader M. Which antidepressants have demonstrated superior efficacy? A review of the evidence. Int Clin Psychopharmacol. 2007;22:323-9.

Papakostas GI. Tolerability of modern antidepressants. J Clin Psychiatry. 2008;69:8-13.

Cloninger CR, Sigvardsson S, Przybeck TR, Svrakic DM. Personality antecedents of alcoholism in a national area probability sample. Eur Arch Psychiatry Clin Neurosci. 1995;245:239-44.

Cloninger CR, Sigvardsson S, Bohman M. Childhood personality predicts alcohol abuse in young adults. Alcohol Clin Exp Res. 1988;12:494-505.

Franken IH, Hendriks VM. Screening and diagnosis of anxiety and mood disorders in substance abuse patients. Am J Addict. 2001;10:30-9.

Kell MJ. Opiate dependence, comorbidity and seasonality of birth. J Addict Dis. 1995;14:19-34.

Milby JB, Sims MK, Khuder S, Schumacher JE, Huggins N, McLellan AT. Psychiatric comorbidity: prevalence in methadone maintenance treatment. Am J Drug Alcohol Abuse. 1996;22:95-107.

Dellu F, Piazza PV, Mayo W, Le Moal M, Simon H. Novelty-seeking in rats-biobehavioral characteristics and possible relationship with the sensation-seeking trait in man. Neuropsychobiology. 1996;34:136-45.

Jama A, Cecchi M, Calvo N, Watson SJ, Akil H. Inter-individual differences in novelty-seeking behavior in rats predict differential responses to desipramine in the forced swim test. Psychopharmacology (Berl). 2008;198:333-40.

Dellu F, Mayo W, Vallée M, Maccari S, Piazza PV, Le Moal M. Behavioral reactivity to novelty during youth as a predictive factor of stress-induced corticosterone secretion in the elderly-a life-span study in rats. Psychoneuroendocrinology. 1996;21:441-53.

Kabbaj M, Akil H. Individual differences in novelty-seeking behavior in rats: a c-fos study. Neuroscience. 2001;106:535-45.

Taghzouti K, Lamarque S, Kharouby M, Simon H. Interindividual differences in active and passive behaviors in the forced-swimming test: implications for animal models of psychopathology. Biol Psychiatry. 1999;45:750-8.

Crosio C, Heitz E, Allis CD, Borrelli E, Sassone-Corsi P. Chromatin remodeling and neuronal response: multiple signaling pathways induce specific histone H3 modifications and early gene expression in hippocampal neurons. J Cell Sci. 2003;116:4905-14.

Ito K, Adcock IM. Histone acetylation and histone deacetylation. Mol Biotechnol. 2002;20:99-106.

Miczek KA, Mos J, Olivier B. Brain 5-HT and inhibition of aggressive behavior in animals: 5-HIAA and receptor subtypes. Psychopharmacol Bull. 1989;25:399-403.

Stein DJ, Miczek KA, Lucion AB, de Almeida RM. Aggression-reducing effects of F15599, a novel selective 5-HT1A receptor agonist, after microinjection into the ventral orbital prefrontal cortex, but not in infralimbic cortex in male mice. Psychopharmacology (Berl). 2013;230:375-87.

Graeff FG. Serotonin, the periaqueductal gray and panic. Neurosci Biobehav Rev. 2004;28:239-59.

Chung KK, Martinez M, Herbert J. Central serotonin depletion modulates the behavioural, endocrine and physiological responses to repeated social stress and subsequent c-fos expression in the brains of male rats. Neuroscience. 1999;92:613-25.

Korte SM, Koolhaas JM, Wingfield JC, McEwen BS. The Darwinian concept of stress: benefits of allostasis and costs of allostatic load and the trade-offs in health and disease. Neurosci Biobehav Rev. 2005;29:3-38.

Koolhaas JM, Korte SM, de Boer SF, Van Der Vegt BJ, Van Reenen CG, Hopster H. Coping styles in animals: current status in behavior and stress-physiology. Neurosci Biobehav Rev. 1999;23:925-35.

Robertson HA, Peterson MR, Murphy K, Robertson GS. D1-dopamine receptor agonists selectively activate striatal c-fos independent of rotational behaviour. Brain Res. 1989;503:346-9.