Trends in Psychiatry and Psychotherapy
https://trends.org.br/article/doi/10.1590/2237-6089-2015-0013
Trends in Psychiatry and Psychotherapy
Original Article

Variables associated with health-related quality of life in a Brazilian sample of patients from a tertiary outpatient clinic for depression and anxiety disorders

Variáveis associadas à qualidade de vida em uma amostra de pacientes de um serviço ambulatorial terciário para transtornos de ansiedade e depressão

Bianca Schwab; Heloisa Silveira Daniel; Carine Lutkemeyer; João Arthur Lange Lins Neves; Louise Nassif Zilli; Ricardo Guarnieri; Alexandre Paim Diaz; Ana Maria Maykot Prates Michels

Downloads: 0
Views: 337

Abstract

Introduction: Health-related quality of life (HRQOL) assessment tools have been broadly used in the medical context. These tools are used to measure the subjective impact of the disease on patients. The objective of this study was to evaluate the variables associated with HRQOL in a Brazilian sample of patients followed up in a tertiary outpatient clinic for depression and anxiety disorders. Method: Cross-sectional study. Independent variables were those included in a sociodemographic questionnaire and the Hospital Anxiety and Depression Scale (HADS) scores. Dependent variables were those included in the short version of the World Health Organization Quality of Life (WHOQOL-BREF) and the scores for its subdomains (overall quality of life and general health, physical health, psychological health, social relationships, and environment). A multiple linear regression analysis was used to find the variables independently associated with each outcome. Results: Seventy-five adult patients were evaluated. After multiple linear regression analysis, the HADS scores were associated with all outcomes, except social relationships (p = 0.08). Female gender was associated with poor total scores, as well as psychological health and environment. Unemployment was associated with poor physical health. Conclusion: Identifying the factors associated with HRQOL and recognizing that depression and anxiety are major factors are essential to improve the care of patients.

Keywords

Quality of life, depression, anxiety

Resumo

Introdução: Instrumentos para avaliar qualidade de vida relacionada à saúde têm sido amplamente utilizados no contexto médico, visando mensurar o impacto da doença de uma perspectiva subjetiva e relevante ao paciente. O objetivo desse estudo foi identificar variáveis associadas à qualidade de vida em uma amostra de pacientes acompanhados em um ambulatório terciário para transtornos de ansiedade e depressão. Métodos: Estudo transversal. As variáveis independentes incluíram dados de um questionário sociodemográfico e pontuação na Escala Hospitalar de Ansiedade e Depressão (HADS). Variáveis dependentes: pontuação total na escala breve de qualidade de vida da Organização Mundial de Saúde (WHOQOL-Bref) e cada um de seus subdomínios (geral, físico, psicológico, social e ambiental). Regressão linear múltipla foi aplicada para identificar as variáveis preditoras associadas de forma independente a cada uma das variáveis dependentes. Resultados: Setenta e cinco pacientes adultos foram avaliados. Após análise de regressão linear múltipla, pontuação na HADS esteve associada com todos os desfechos analisados, exceto para o subdomínio social (p = 0,08). Sexo feminino esteve negativamente associado com a pontuação total da WHOQOL-Bref e com os subdomínios psicológico e ambiental. Desemprego esteve associado com o subdomínio físico. Conclusão: A identificação de fatores associados à qualidade de vida relacionada à saúde e o reconhecimento de que a depressão e a ansiedade são variáveis fundamentais são essenciais para uma melhor assistência aos pacientes.

Palavras-chave

Qualidade de vida, depressão, ansiedade

References

Strawbridge WJ. Quality of life: what is it and can it be measured?. Growth Horm IGF Res. 1998;8:59-62.

Berlim MT, Fleck MP. "Quality of life": a brand new concept for research and practice in psychiatry. Rev Bras Psiquiatr. 2003;25:249-52.

Schuepbach WM, Rau J, Knudsen K, Volkmann J, Krack P, Timmermann L. Neurostimulation for Parkinson's disease with early motor complications. N Engl J Med. 2013;368:610-22.

Mendlowicz MV, Stein MB. Quality of life in individuals with anxiety disorders. Am J Psychiatry. 2000;157:669-82.

Gustavsson A, Svensson M, Jacobi F, Allgulander C, Alonso J, Beghi E. Cost of disorders of the brain in Europe 2010. Eur Neuropsychopharmacol. 2011;21:718-79.

Rocha NS, Fleck MP. Evaluation of quality of life in adults with chronic health conditions: the role of depressive symptoms. Rev Bras Psiquiatr. 2010;32:119-24.

Cretu RZ, David AM. Comparative study: the quality of life of patients with leukemia, anxiety and depressive disorders. Procedia Soc Behav Sci. 2014;127:883-6.

Fleck MP, Lima AF, Louzada S, Schestasky G, Henriques A, Borges VR. [Association of depressive symptoms and social functioning in primary care service, Brazil]. Rev Saude Publica. 2002;36:431-8.

Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67:361-70.

Botega NJ, Bio MR, Zomignani MA, Garcia C Jr, Pereira WA. [Mood disorders among inpatients in ambulatory and validation of the anxiety and depression scale HAD]. Rev Saude Publica. 1995;29:355-63.

Kessler RC, Sampson NA, Berglund P, Gruber MJ, Al-Hamzawi A, Andrade L. Anxious and non-anxious major depressive disorder in the World Health Organization World Mental Health Surveys. Epidemiol Psychiatr Sci. 2015;27:1-17.

Skevington SM, Lotfy M. The World Health Organization's WHOQOL-BREF quality of life assessment: psychometric properties and results of the international field trial. A report from the WHOQOL group. Qual Life Res. 2004;13:299-310.

Berlim MT, Pavanello DP, Caldieraro MA, Fleck MP. Reliability and validity of the WHOQOL BREF in a sample of Brazilian outpatients with major depression. Qual Life Res. 2005;14:561-4.

Olsson I, Mykletun A, Dahl AA. The Hospital Anxiety and Depression Rating Scale: a cross-sectional study of psychometrics and case finding abilities in general practice. BMC Psychiatry. 2005;5:46.

Daly EJ, Trivedi MH, Wisniewski SR, Nierenberg AA, Gaynes BN, Warden D. Health-related quality of life in depression: a STAR*D report. Ann Clin Psychiatry. 2010;22:43-55.

Nyer M, Kasckow J, Fellows I, Lawrence EC, Golshan S, Solorzano E. The relationship of marital status and clinical characteristics in middle-aged and older patients with schizophrenia and depressive symptoms. Ann Clin Psychiatry. 2010;22:172-9.

Stroppa A, Moreira-Almeida A. Religiosity, mood symptoms, and quality of life in bipolar disorder. Bipolar Disord. 2013;15:385-93.

Brett CE, Gow AJ, Corley J, Pattie A, Starr JM, Deary IJ. Psychosocial factors and health as determinants of quality of life in community-dwelling older adults. Qual Life Res. 2012;21:505-16.

Al-Fayez GA, Ohaeri JU. Profile of subjective quality of life and its correlates in a nation-wide sample of high school students in an Arab setting using the WHOQOL-Bref. BMC Psychiatry. 2011;11:71.

Iacoponi E, Mari JJ. Reliability and factor structure of the Portuguese version of Self-Reporting Questionnaire. Int J Soc Psychiatry. 1989;35:213-22.

Ware Jr JE, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care. 1992;30:473-83.

Galvao LL, Farias MC, de Azevedo PR, Vilar MJ, de Azevedo GD. [Prevalence of mental disorders and assessment of quality of life in the climaterium]. Rev Assoc Med Bras. 2007;53:414-20.

Portugal FB, Campos MR, Gonçalves DA, Mari JJ, Gask L, Bower P. Psychiatric morbidity and quality of life of primary care attenders in two cities in Brazil. J Bras Psiquiatr. 2014;63:23-32.

D'Avanzato C, Martinez J, Attiullah N, Friedman M, Toba C, Boerescu DA. Anxiety symptoms among remitted depressed outpatients: prevalence and association with quality of life and psychosocial functioning. J Affect Disord. 2013;151:401-4.

Berber JS, Kupek E, Berber SC. Prevalência de depressão e sua relação com a qualidade de vida em pacientes com síndrome da fibromialgia. Rev Bras Reumatol. 2005;45:47-54.

Jansen K, Mondin TC, Ores Lda C, Souza LD, Konradt CE, Pinheiro RT. [Mental common disorders and quality of life in young adulthoods: a population-based sample in Pelotas, Rio Grande do Sul State, Brazil]. Cad Saude Publica. 2011;27:440-8.

Mental health: the great depression. Nature. 2014;515:179.

The burden of depression. Nature. 2014;515:163.

Pucci G, Reis RS, Rech CR, Hallal PC. Quality of life and physical activity among adults: population-based study in Brazilian adults. Qual Life Res. 2012;21:1537-43.

Omorou YA, Erpelding ML, Escalon H, Vuillemin A. Contribution of taking part in sport to the association between physical activity and quality of life. Qual Life Res. 2013;22:2021-9.

Ardeshna KM, Qian W, Smith P, Braganca N, Lowry L, Patrick P. Rituximab versus a watch-and-wait approach in patients with advanced-stage, asymptomatic, non-bulky follicular lymphoma: an open-label randomised phase 3 trial. Lancet Oncol. 2014;15:424-35.

6169f7afa9539563b1104782 trends Articles
Links & Downloads

Trends Psychiatry Psychother

Share this page
Page Sections