The future of psychiatric research
O futuro da pesquisa em psiquiatria
Marco Antonio Caldieraro
Abstract
Keywords
Resumo
Palavras-chave
References
Whiteford HA, Degenhardt L, Rehm J, Baxter AJ, Ferrari AJ, Erskine HE. Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010. Lancet. 2013;382:1575-86.
NIMH strategic plan for research. 2015.
Wykes T, Haro JM, Belli SR, Obradors-Tarragó C, Arango C, Ayuso-Mateos JL. Mental health research priorities for Europe. Lancet Psychiatry. 2015;2:1036-42.
Cuthbert BN, Insel TR. BMC Med. 2013;11:126.
Preventing suicide: a global imperative. 2014.
Kendler KS. Explanatory models for psychiatric illness. Am J Psychiatry. 2008;165:695-702.
Kim YS, State MW. Recent challenges to the psychiatric diagnostic nosology: a focus on the genetics and genomics of neurodevelopmental disorders. Int J Epidemiol. 2014;43:465-75.
Ostergaard SD, Jensen SO, Bech P. The heterogeneity of the depressive syndrome: when numbers get serious. Acta Psychiatr Scand. 2011;124:495-6.
Parker G, Paterson A. Melancholia: definition and management. Curr Opin Psychiatry. 2014;27:1-6.
Regier DA, Narrow WE, Clarke DE, Kraemer HC, Kuramoto SJ, Kuhl EA. DSM-5 field trials in the United States and Canada, Part II: test-retest reliability of selected categorical diagnoses. Am J Psychiatry. 2013;170:59-70.
Insel TR. The NIMH Research Domain Criteria (RDoC) Project: precision medicine for psychiatry. Am J Psychiatry. 2014;171:395-7.
Collins PY, Patel V, Joestl SS, March D, Insel TR, Daar AS. Grand challenges in global mental health. Nature. 2011;475:27-30.
Cohen-Woods S, Craig IW, McGuffin P. The current state of play on the molecular genetics of depression. Psychol Med. 2013;43:673-87.
McClellan J, King MC. Genomic analysis of mental illness: a changing landscape. JAMA. 2010;303:2523-4.
Flint J, Kendler KS. The genetics of major depression. Neuron. 2014;81:484-503.
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. Nat Neurosci. 2015;18:199-209.
Arnedo J, Svrakic DM, Del Val C, Romero-Zaliz R, Hernández-Cuervo H. Uncovering the hidden risk architecture of the schizophrenias: confirmation in three independent genome-wide association studies. Am J Psychiatry. 2015;172:139-53.
Duncan LE, Keller MC. A critical review of the first 10 years of candidate gene-by-environment interaction research in psychiatry. Am J Psychiatry. 2011;168:1041-9.
Gelernter J. Genetics of complex traits in psychiatry. Biol Psychiatry. 2015;77:36-42.
Papassotiropoulos A, Fountoulakis M, Dunckley T, Stephan DA, Reiman EM. Genetics, transcriptomics, and proteomics of Alzheimer's disease. J Clin Psychiatry. 2006;67:652-70.
Cao M, Wang Z, He Y. Connectomics in psychiatric research: advances and applications. Neuropsychiatr Dis Treat. 2015;11:2801-10.
Mei H, Xia T, Feng G, Zhu J, Lin SM, Qiu Y. Opportunities in systems biology to discover mechanisms and repurpose drugs for CNS diseases. Drug Discov Today. 2012;17:1208-16.
Tretter F, Winterer G, Gebicke-Haerter PJ, Mendoza ER. Systems biology in psychiatric research. 2010.
Wang W, Krishnan E. Big data and clinicians: a review on the state of the science. JMIR Med Inform. 2014;2:e1.
Sejnowski TJ, Churchland PS, Movshon JA. Putting big data to good use in neuroscience. Nat Neurosci. 2014;17:1440-1.
Monteith S, Glenn T, Geddes J, Bauer M. Big data are coming to psychiatry: a general introduction. Int J Bipolar Disord. 2015;3:21.
Paus T. Population neuroscience: why and how. Hum Brain Mapp. 2010;31:891-903.
Casey BJ, Oliveri ME, Insel T. A neurodevelopmental perspective on the research domain criteria (RDoC) framework. Biol Psychiatry. 2014;76:350-3.
McInnis MG, Greden JF. Longitudinal studies: an essential component for complex psychiatric disorders. Neuroscie Res. 2016;102:4-12.
Salum GA, Gadelha A, Pan PM, Moriyama TS, Graeff-Martins AS, Tamanaha AC. High risk cohort study for psychiatric disorders in childhood: rationale, design, methods and preliminary results. Int J Methods Psychiatr Res. 2015;24:58-73.
DuBois JM, Bailey-Burch B, Bustillos D, Campbell J, Cottler L, Fisher CB. Ethical issues in mental health research: the case for community engagement. Curr Opin Psychiatry. 2011;24:208-14.