Trends in Psychiatry and Psychotherapy
https://trends.org.br/article/doi/10.1590/2237-6089-2017-0153
Trends in Psychiatry and Psychotherapy
Review Article

Does CBT have lasting effects in the treatment of PTSD after one year of follow-up? A systematic review of randomized controlled trials

A TCC possui efeitos duradouros no tratamento do TEPT após um ano de seguimento? Revisão sistemática de ensaios clínicos randomizados

Tânia Macedo; Marllon Barbosa; Helga Rodrigues; Evandro da Silva Freire Coutinho; Ivan Figueira; Paula Ventura

Downloads: 0
Views: 359

Abstract

Abstract Introduction: While several previous meta-analyses have documented the short-term efficacy of cognitive-behavioral therapy (CBT), its long-term efficacy remains unknown. Posttraumatic stress disorder (PTSD) is a serious, debilitating, often chronic and disabling disease. Objective: To estimate the long-term efficacy of CBT in the treatment of PTSD by assessing the maintenance of the effect after one year of follow-up. Method: We performed a systematic review through electronic database searches including ISI Web of Science, PubMed, PsycInfo and Pilots. We included randomized studies in which CBT was compared with a control group (waiting list or usual care) in adults with PTSD that reported at least one year of CBT follow-up. Results: Our search identified 2,324 studies and 8 were selected. CBT was shown to be effective in the treatment of PTSD in the post-treatment period. Improvement in PTSD symptoms was statistically significant in relation to the control group. The improvement observed in the treatment group or single group (formed by both treatment group and control group, which was submitted to the intervention after a few weeks on the waiting list) was maintained in the follow-up. Conclusion: Due to the lack of control groups in the follow-up period in six of the eight studies included in this review, there is still no proper methodological basis to assert that CBT has lasting effects in the treatment of PTSD. Our study found serious methodological shortcomings and the need to fill this gap in the literature through the development of studies with robust and sophisticated designs.

Keywords

Post-traumatic stress disorder, cognitive-behavioral therapy, follow-up, lasting effects

Resumo

Resumo Introdução: Várias meta-análises anteriores documentaram a eficácia a curto prazo da terapia cognitivo-comportamental (TCC). No entanto, sua eficácia a longo prazo permanece desconhecida. O transtorno de estresse pós-traumático (TEPT) é uma doença crônica grave, debilitante e incapacitante. Objetivo: Estimar a eficácia a longo prazo da TCC no tratamento do TEPT, avaliando a manutenção do efeito após um ano de seguimento. Métodos: Realizamos uma revisão sistemática através de pesquisas nas bases de dados eletrônicas ISI Web of Science, PubMed, PsycInfo e Pilots. Incluímos estudos randomizados nos quais a TCC foi comparada com um grupo controle (lista de espera ou tratamento usual) em adultos com TEPT que relataram pelo menos um ano de seguimento da TCC. Resultados: A pesquisa identificou 2.324 estudos e 8 foram selecionados. A TCC mostrou-se eficaz no tratamento do TEPT no período pós-tratamento. A melhora nos sintomas de TEPT foi estatisticamente significativa em relação ao grupo controle. A melhora observada no grupo de tratamento ou grupo único (formado por ambos os grupos de tratamento e controle, que foi submetido à intervenção após algumas semanas na lista de espera) foi mantida no seguimento. Conclusão: Devido à ausência de grupo controle no período de follow-up em 6 dos 8 estudos incluídos nesta revisão, ainda não há base metodológica adequada para afirmar que a TCC tem efeitos duradouros no tratamento do TEPT. Nosso estudo encontrou graves deficiências metodológicas e a necessidade de preencher essa lacuna na literatura através de estudos com delineamentos robustos e sofisticados.

Palavras-chave

Transtorno de estresse pós-traumático, terapia cognitivo-comportamental, seguimento, efeitos duradouros

References

Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE. Lifetime prevalence and age-of-onset distributions of. Arch Gen Psychiatry. 2005;62:593-602.

Pagotto LF, Mendlowicz MV, Coutinho ESF, Figueira I, Luz MP, Araujo AX. The impact of posttraumatic symptoms and comorbid mental disorders on the health-related quality of life in treatment-seeking PTSD patients. Compr Psychiatry. 2015;58:68-73.

Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). 2013.

Cuijpers P, Cristea IA, Karyotaki E, Reijnders M, Huibers MJH. How effective are cognitive behavior therapies for major depression and anxiety disorders? A meta-analytic update of the evidence. World Psychiatry. 2016;15:245-58.

Cusack K, Jonas DE, Forneris CA, Wines C, Sonis J, Middleton JC. Psychological treatments for adults with posttraumatic stress disorder: A systematic review and meta-analysis. Clin Psychol Rev. 2016;43:128-41.

Bisson JI, Ehlers A, Matthews R, Pilling S, Richards D, Turner S. Psychological treatments for chronic post-traumatic stress disorder Systematic review and meta-analysis. Br J Psychiatry. 2007;190:97-104.

Bisson JI, Roberts NP, Andrew M, Cooper R, Lewis C. Psychological therapies for chronic post-traumatic stress disorder (PTSD) in adults. Cochrane Database Syst Rev. 2013;12:1-248.

The global burden of disease: 2004 update. 2008:1-146.

Hollon SD, Stewart MO, Strunk D. Enduring effects for cognitive behavior therapy in the treatment of depression and anxiety. Annu Rev Psychol. 2006;57:285-315.

Flückiger C, Del Re AC, Munder T, Heer S, Wampold BE. Enduring effects of evidence-based psychotherapies in acute depression and anxiety disorders versus treatment as usual at follow-up - A longitudinal meta-analysis. Clin Psychol Rev. 2014;34:367-75.

Higgins JPT, Altman DG, Gotzsche PC, Juni P, Moher D, Oxman AD. The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. Bmj. 2011;343:889-93.

Review Manager (RevMan) Version 5.3 [computer program]. Cochrane Community. 2014.

Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JPA. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. Ann Intern Med. 2009;151:65-94.

Asukai N, Saito A, Tsuruta N, Kishimoto J, Nishikawa T. Efficacy of exposure therapy for Japanese patients with posttraumatic stress disorder due to mixed traumatic events: a randomized controlled study. J Trauma Stress. 2010;23:744-50.

Chard KM. An evaluation of cognitive processing therapy for the treatment of posttraumatic stress disorder related to childhood sexual abuse. J Consult Clin Psychol. 2005;73:965-71.

Foa EB, Dancu CV, Hembree EA, Jaycox LH, Meadows EA, Street GP. A comparison of exposure therapy, stress inoculation training, and their combination for reducing posttraumatic stress disorder in female assault victims. J Consult Clin Psychol. 1999;67:194-200.

Foa EB, Hembree EA, Cahill SP, Rauch SAM, Riggs DS, Feeny NC. Randomized trial of prolonged exposure for posttraumatic stress disorder with and without cognitive restructuring: outcome at academic and community clinics. J Consult Clin Psychol. 2005;73:953-64.

Knaevelsrud C, Maercker A. Long-term effects of an internet-based treatment for posttraumatic stress. Cogn Behav Ther. 2010;39:72-7.

Mueser KT, Gottlieb JD, Xie H, Lu W, Yanos PT, Rosenberg SD. Evaluation of cognitive restructuring for post-traumatic stress disorder in people with severe mental illness. Br J Psychiatry. 2015;206:501-8.

Nacasch N, Foa EB, Huppert JD, Tzur D, Fostick L, Dinstein Y. Prolonged exposure therapy for combat- and terror-related posttraumatic stress disorder: A randomized control comparison with treatment as usual. J Clin Psychiatry. 2011;72:1174-80.

Power K, McGoldrick T, Brown K, Buchanan R, Sharp D, Swanson V. A controlled comparison of eye movement desensitization and reprocessing versus exposure plus cognitive restructuring versus waiting list in the treatment of post-traumatic stress disorder. Clin Psychol Psychother. 2002;9:299-318.

Bradley R, Greene J, Russ E, Dutra L, Westen D. A multidimensional meta-analysis of psychotherapy for PTSD. Am J Psychiatry. 2005;162:214-27.

Sijbrandij M, Kunovski I, Cuijpers P. Effectiveness of internet-delivered cognitive behavioral therapy for posttraumatic stress disorder: a systematic review and meta-analysis. Depress Anxiety. 2016;33:783-91.

Mohr DC, Spring B, Freedland KE, Beckner V, Arean P, Hollon SD. The selection and design of control conditions for randomized controlled trials of psychological interventions. Psychother Psychosom. 2009;78:275-84.

Beshai S, Dobson KS, Bockting CLH, Quigley L. Clinical psychology review relapse and recurrence prevention in depression: current research and future prospects. Clin Psychol Rev. 2011;31:1349-60.

Morina N, Wicherts JM, Lobbrecht J, Priebe S. Remission from post-traumatic stress disorder in adults: a systematic review and meta-analysis of long term outcome studies. Clin Psychol Rev. 2014;34:249-55.

6169c95ca95395528b27f393 trends Articles
Links & Downloads

Trends Psychiatry Psychother

Share this page
Page Sections