Trends in Psychiatry and Psychotherapy
https://trends.org.br/article/doi/10.1590/S2237-60892012000300008
Trends in Psychiatry and Psychotherapy
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Low serum levels of 25-hydroxyvitamin D (25-OHD) in children with autism

Baixos níveis séricos de 25-hidroxivitamina D (25-OHD) em crianças com autismo

Márcia Helena Fávero de Souza Tostes; Hudson Caetano Polonini; Wagner Farid Gattaz; Nádia Rezende Barbosa Raposo; Edilene Bolutari Baptista

http://dx.doi.org/10.1590/S2237-60892012000300008 Trends Psychiatry Psychother, vol.34, n3, p.161-163, 2012
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Abstract

Objective: To confirm previous evidence suggesting an association between autism and low vitamin D serum levels. Methods: This preliminary exploratory study assessed the circulating levels of 25-hydroxyvitamin D (25-OHD) in pediatric patients with autism and in typically developing controls from Juiz de Fora, Brazil. Results: Serum levels of 25-OHD were lower in children with autism (26.48 ± 3.48 ng mL-1) when compared to typically developing subjects (40.52 ± 3.13 ng mL-1) (p < 0.001). Conclusion: Our findings attest to the importance of vitamin supplementation during pregnancy and in the treatment of children with autism, who tend to present low vitamin D consumption rates.

Keywords

Autism, children, vitamin D

Resumo

Objetivo: Confirmar evidências prévias indicando uma associação entre autismo e baixos níveis séricos de vitamina D. Métodos: Este estudo preliminar avaliou os níveis circulantes de 25-hidroxivitamina D (25-OHD) em pacientes pediátricos com autismo e em controles apresentando desenvolvimento típico em Juiz de Fora, Brasil. Resultados: Os níveis séricos de 25-OHD foram menores em crianças com autismo (26,48 ± 3,48 ng mL-1) em comparação com indivíduos com desenvolvimento típico (40,52 ± 3,13 ng mL-1) (p < 0,001). Conclusão: Nossos resultados confirmam a importância da suplementação de vitamina durante a gravidez e no tratamento de crianças com autismo, que costumam apresentar um baixo consumo de vitamina D.

Palavras-chave

Autismo, crianças, vitamina D

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