Trends in Psychiatry and Psychotherapy
https://trends.org.br/article/doi/10.47626/2237-6089-2020-0024
Trends in Psychiatry and Psychotherapy
Original Article

Early trauma and schizophrenia onset: preliminary results of an outpatient cohort in Brazil

Leandro de Oliveira Trovão, Gilberto Sousa Alves, Carolina Gomes Carrilho, Thaysse Gomes Ricci, Lays Bittencourt, Cândida Alves, Natália Costa Brito, Antonio Egídio Nardi, Dolores Malaspina, André Barciela Veras

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Abstract

Objectives
To assess the prevalence of early trauma in individuals with onset of schizophrenia (SZ) at early (≤ 18 years) and adult (> 18 years) ages (EOP and AOP, respectively) and explore relationships between the onset of disease and clinical variables including traumatic events and psychotic and mood symptoms.

Methods
Subjects with SZ (n = 71) and EOP and AOP were compared for history of psychological trauma, sexual abuse, and physical punishment using the Early Trauma Inventory Self Report - Short Form (ETISR-SF). They were also compared for history of comorbidities and affective disorders using the Diagnostic Interview for Psychosis and Affective Disorders, the Positive and Negative Syndrome Scale, the Liebowitz Social Anxiety Scale, and the Calgary Depression Scale for Schizophrenia. Coefficients were calculated for correlations between scale results and disease duration.

Results
Early trauma was significantly associated with an early onset psychotic episode (r = -0.315, p < 0.01). General trauma and depressive symptoms in adulthood were also associated (r = 0.442, p < 0.01), as were social anxiety symptoms and early trauma (r = 0.319, p < 0.01). Total ETISR-SF scores and the physical abuse item were significantly higher in EOP than in AOP. In the hierarchical regression, PANSS scores were best predicted by a model including the duration of disease and age of first psychotic episode (R = 0.303).

Conclusions
Our results support the hypothesis that early trauma, including physical abuse, may play a relevant role in schizophrenia symptoms, such as an earlier psychotic occurrence, as well as features of other psychiatric disorders, such as greater severity of social anxiety and depression.

Keywords

Early trauma, schizophrenia, abuse, depression

Submitted date:
02/29/2020

Accepted date:
04/12/2021

637298e5a9539571592822f4 trends Articles
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