Trends in Psychiatry and Psychotherapy
https://trends.org.br/article/doi/10.1590/2237-6089-2014-0063
Trends in Psychiatry and Psychotherapy
Review Article

The role of memory in posttraumatic stress disorder: implications for clinical practice

O papel da memória no transtorno de estresse pós-traumático: implicações para a prática clínica

Marcelo Montagner Rigoli; Gustavo Ramos Silva; Fernando Rainho de Oliveira; Giovanni Kuckartz Pergher; Christian Haag Kristensen

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Abstract

Abstract Introduction: Posttraumatic stress disorder (PTSD) is a highly prevalent disorder with important social consequences. Several models have been developed with the aim of understanding the mechanisms underlying its symptoms. Intrusions are idiosyncratic symptoms that commonly take the form of involuntary recollection of images or flashbacks about the traumatic event. Objective: To review how memory is conceptualized in each of these models and the implications for clinical practice. Methods: A narrative review of the literature was conducted through analysis of the perspectives of memory in theoretical models of PTSD. Results: Two main perspectives were identified: 1) models in which specific mechanisms of memory for processing traumatic events are proposed, especially those based on clinical studies, and 2) models in which common mnemonic mechanisms are utilized to explain the phenomenon, primarily based on basic experimental research studies investigating memory. The different theories based on these approaches have led to distinct psychotherapy interventions. Conclusion: In order to clarify these discrepancies, future research should aim for the methodological rigor of experimental studies, while maintaining the ecological applicability of findings. Cognitive experimental psychopathology is therefore an area on which research funding should be focused. Such studies could elucidate the role of mnemonic aspects in PTSD and how they impact psychological treatments.

Keywords

Posttraumatic stress disorder, memory, experimental psychopathology, cognitive therapy

Resumo

Resumo Introdução: O transtorno de estresse pós-traumático (TEPT) é altamente prevalente e traz consequências sociais importantes. Diversos modelos foram desenvolvidos com o objetivo de compreender os mecanismos subjacentes aos seus sintomas. Intrusões constituem sintomas idiossincráticos, que regularmente tomam a forma de lembranças involuntárias de imagens ou flashbacks do evento traumático. Objetivo: Revisar como a memória é definida conceitualmente nos modelos teóricos propostos e as implicações para a prática clínica. Métodos: Uma revisão narrativa da literatura foi conduzida através da análise das perspectivas de memória em modelos teóricos de TEPT. Resultados: Duas perspectivas principais foram identificadas: 1) modelos com a proposição de mecanismos de memória específicos ao processamento de eventos traumáticos, especialmente apoiados em estudos clínicos, e 2) modelos em que mecanismos mnemônicos comuns são utilizados para explicar o fenômeno, primariamente baseados em estudos experimentais de base investigando memória. As diferentes teorias baseadas nessas perspectivas levaram a distintas abordagens psicoterapêuticas. Conclusões: Para clarificar essas discrepâncias, sugere-se que pesquisas futuras busquem maior rigor metodológico de estudos experimentais, mantendo a aplicabilidade ecológica dos achados. A psicopatologia cognitiva experimental é uma área na qual devem ser focados os financiamentos de pesquisa. Tais estudos podem elucidar o papel de aspectos mnemônicos no TEPT e como impactam tratamentos psicológicos.

Palavras-chave

Transtorno de estresse pós-traumático, memória, psicopatologia experimental, terapia cognitiva

References

Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR). 2000.

Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). 2013.

Brewin CR. Episodic memory, perceptual memory, and their interaction foundations for a theory of posttraumatic stress disorder. Psychol Bull. 2014;140:69-97.

Rubin DC, Boals A, Berntsen D. Memory in posttraumatic stress disorder properties of voluntary and involuntary, traumatic and nontraumatic autobiographical memories in people with and without posttraumatic stress disorder symptoms. J Exp Psychol Gen. 2008;137:591-614.

Brewin CR, Dalgleish T, Joseph S. A dual representation theory of posttraumatic stress disorder. Psychol Rev. 1996;103:670-86.

Ehlers A, Clark DM. A cognitive model of posttraumatic stress disorder. Behav Res Ther. 2000;38:319-45.

Foa EB, Kozak MJ. Emotional processing of fear exposure to corrective information. Psychol Bull. 1986;99:20-35.

Shobe KK, Kihlstrom JF. Is traumatic memory special. Curr Dir Psychol Sci. 1997;6:70-4.

Rubin DC, Berntsen D, Bohni MK. A memory-based model of posttraumatic stress disorder evaluating basic assumptions underlying the PTSD diagnosis. Psychol Rev. 2008;115:985-1011.

Gunnar M, Quevedo K. The neurobiology of stress and development. Annu Rev Psychol. 2007;58:145-73.

Yehuda R, LeDoux J. Response variation following trauma a translational neuroscience approach to understanding PTSD. Neuron. 2007;56:19-32.

Breslau N. Epidemiologic studies of trauma, posttraumatic stress disorder, and other psychiatric disorders. Can J Psychiatry. 2002;47:923-9.

Ogle CM, Rubin DC, Berntsen D, Siegler IC. The frequency and impact of exposure to potentially traumatic events over the life course. Clin Psychol Sci. 2013;1:426-34.

Santiago PN, Ursano RJ, Gray CL, Pynoos RS, Spiegel D, Lewis-Fernandez R. A systematic review of PTSD prevalence and trajectories in DSM-5 defined trauma exposed populations intentional and non-intentional traumatic events. PLoS One. 2013;8:e59236.

Keane TM, Marshall AD, Taft CT. Posttraumatic stress disorder etiology, epidemiology, and treatment outcome. Annu Rev Clin Psychol. 2006;2:161-97.

Kessler RC. The national comorbidity survey preliminary results and future directions. Int J Methods Psychiatr Res. 1995;5:139-51.

Kessler RC, Chiu WT, Demler O, Merikangas KR, Walters EE. Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry. 2005;62:617-27.

Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry. 2005;62:593-602.

Kessler RC. Gender differences in major depression: epidemiological findings. Gender and its effects on psychopathology. American Psychopathological Association Series. 2000:61-84.

Olatunji BO, Cisler JM, Tolin DF. Quality of life in the anxiety disorders a meta-analytic review. Clin Psychol Rev. 2007;27:572-81.

Schaefer LS, Lobo B de OM, Kristensen CH. Transtorno de estresse pós-traumático decorrente de acidente de trabalho implicações psicológicas, socioeconômicas e jurídicas. Estud Psicol (Natal). 2012;17:329-36.

Taylor S. Clinician's guide to PTSD: a cognitive-behavioral approach. 2006.

Walker EA, Katon W, Russo J, Ciechanowski P, Newman E, Wagner AW. Health care costs associated with posttraumatic stress disorder symptoms in women. Arch Gen Psychiatry. 2003;60:369-74.

Brewin CR, Andrews B, Valentine JD. Meta-analysis of risk factors for posttraumatic stress disorder in trauma-exposed adults. J Consult Clin Psychol. 2000;68:748-66.

Ozer EJ, Best SR, Lipsey TL, Weiss DS. Predictors of posttraumatic stress disorder and symptoms in adults a meta-analysis. Psychol Bull. 2003;129:52-73.

Diagnostic and Statistical Manual of Mental Disorders, Third Revised Edition (DSM-III-R). 1987.

Mowrer OH. On the dual nature of learning-a re-interpretation of "conditioning" and "problem-solving " Harv Educ. Rev. 1947;17:102-48.

Horowitz MJ. Stress response syndromes: PTSD, grief, and adjustment disorders. 3rd edition. 1997.

Janoff-Bulman R. Shattered assumptions. 2010.

Jones JC, Barlow DH. The etiology of posttraumatic stress disorder. Clin Psychol Rev. 1990;10:299-328.

Jones JC, Barlow DH. A new model of posttraumatic stress disorder: implications for the future. Posttraumatic stress disorder: a behavioral approach to assessment and treatment. 1992:147-65.

Brewin CR, Holmes EA. Psychological theories of posttraumatic stress disorder. Clin Psychol Rev. 2003;23:339-76.

Rubin DC. A basic-systems approach to autobiographical memory. Curr Dir Psychol Sci. 2005;14:79-83.

Keane TM, Fairbank JA, Caddell JM, Zimering RT, Bender ME. A behavioral approach to assessing and treating post-traumatic stress disorder in Vietnam veterans. Trauma and its wake: the study and treatment of post-traumatic stress disorder. 1985:257-94.

Foa EB, Zinbarg R, Rothbaum BO. Uncontrollability and unpredictability in post-traumatic stress disorder an animal model. Psychol Bull. 1992;112:218-38.

Zovkic IB, Sweatt JD. Epigenetic mechanisms in learned fear implications for PTSD. Neuropsychopharmacology. 2013;38:77-93.

Taylor S, Thordarson DS, Maxfield L, Fedoroff IC, Lovell K, Ogrodniczuk J. Comparative efficacy, speed, and adverse effects of three PTSD treatments exposure therapy, EMDR, and relaxation training. J Consult Clin Psychol. 2003;71:330-8.

Rescorla RA. Pavlovian conditioning It's not what you think it is. Am Psychol. 1988;43:151-60.

Foa E, Hembree E, Rothbaum BO. Prolonged exposure therapy for PTSD: emotional processing of traumatic experiences therapist guide. 2007.

Lang PJ. Imagery in therapy an information processing analysis of fear. Behav Ther. 1977;8:862-86.

Foa EB, Rothbaum BO. Treating the trauma of rape: cognitive-behavioral therapy for PTSD. 2001.

Dunmore E, Clark DM, Ehlers A. Cognitive factors involved in the onset and maintenance of posttraumatic stress disorder (PTSD) after physical or sexual assault. Behav Res Ther. 1999;37:809-29.

Jayawickreme N, Cahill SP, Riggs DS, Rauch SA, Resick PA, Rothbaum BO. Primum non nocere (first do no harm) symptom worsening and improvement in female assault victims after prolonged exposure for PTSD. Depress Anxiety. 2014;31:412-9.

Ehlers A, Clark DM, Hackmann A, McManus F, Fennell M. Cognitive therapy for post-traumatic stress disorder development and evaluation. Behav Res Ther. 2005;43:413-31.

Ehlers A, Clark DM, Hackmann A, McManus F, Fennell M, Herbert C. A randomized controlled trial of cognitive therapy, a self-help booklet, and repeated assessments as early interventions for posttraumatic stress disorder. Arch Gen Psychiatry. 2003;60:1024-32.

Laposa JM, Alden LE. The effect of pre-existing vulnerability factors on a laboratory analogue trauma experience. J Behav Ther Exp Psychiatry. 2008;39:424-35.

Holmes EA, James EL, Kilford EJ, Deeprose C. Key steps in developing a cognitive vaccine against traumatic flashbacks visuospatial Tetris versus verbal Pub Quiz. PLoS One. 2010;5:e13706.

Holmes EA, James EL, Coode-Bate T, Deeprose C. Can playing the computer game "Tetris" reduce the build-up of flashbacks for trauma A proposal from cognitive science. PLoS One. 2009;4:e4153.

Nandrino JL, Pezard L, Posté A, Réveillère C, Beaune D. Autobiographical memory in major depression a comparison between first-episode and recurrent patients. Psychopathology. 2002;35:335-40.

Scott J, Stanton B, Garland A, Ferrier IN. Cognitive vulnerability in patients with bipolar disorder. Psychol Med. 2000;30:467-72.

Williams JM, Broadbent K. Autobiographical memory in suicide attempters. J Abnorm Psychol. 1986;95:144-9.

Rubin DC. The basic-systems model of episodic memory. Perspect Psychol Sci. 2006;1:277-311.

Larsson M, Willander J. Autobiographical odor memory. Ann N Y Acad Sci. 2009;1170:318-23.

Rubin DC, Dennis MF, Beckham JC. Autobiographical memory for stressful events the role of autobiographical memory in posttraumatic stress disorder. Conscious Cogn. 2011;20:840-56.

McNally RJ. Experimental approaches to cognitive abnormality in posttraumatic stress disorder. Clin Psychol Rev. 1998;18:971-82.

Bryant RA, Harvey AG. Attentional bias in posttraumatic stress disorder. J Trauma Stress. 1997;10:635-44.

Pineles SL, Shipherd JC, Welch LP, Yovel I. The role of attentional biases in PTSD is it interference or facilitation?. Behav Res Ther. 2007;45:1903-13.

Cohen H, Benjamin J, Geva A, Matar M, Kaplan Z, Kotler M. Autonomic dysregulation in panic disorder and in post-traumatic stress disorder application of power spectrum analysis of heart rate variability at rest and in response. Psychiatry Res. 2000;96:1-13.

Lindauer RT, van Meijel EP, Jalink M, Olff M, Carlier IV, Gersons BP. Heart rate responsivity to script-driven imagery in posttraumatic stress disorder specificity of response and effects of psychotherapy. Psychosom Med. 2006;68:33-40.

Sack M, Hopper JW, Lamprecht F. Low respiratory sinus arrhythmia and prolonged psychophysiological arousal in posttraumatic stress disorder Heart rate dynamics and individual differences in arousal regulation. Biol Psychiatry. 2004;55:284-90.

Tan G, Dao TK, Farmer L, Sutherland RJ, Gevirtz R. Heart rate variability (HRV) and posttraumatic stress disorder (PTSD) a pilot study. Appl Psychophysiol Biofeedback. 2011;36:27-35.

Bryant RA, Guthrie RM. Maladaptive self-appraisals before trauma exposure predict posttraumatic stress disorder. J Consult Clin Psychol. 2007;75:812-5.

Morgan 3rd CA, Hazlett G, Doran A, Garrett S, Hoyt G, Thomas P. Accuracy of eyewitness memory for persons encountered during exposure to highly intense stress. Int J Law Psychiatry. 2004;27:265-79.

Forsyth JP, Zvolensky MJ. Experimental psychopathology, clinical science, and practice an irrelevant or indispensable alliance?. Appl Prev Psychol. 2002;10:243-64.

Zvolensky MJ, Lejuez CW, Stuart GL, Curtin J. Experimental psychopathology in psychological science. Rev Gen Psychol. 2001;5:371-81.

Lakatos I. Falsification and the methodology of scientific research programmes. Can theories be refuted?. 1975:205-59.

Popper KR. The logic of scienti?c discovery. 1959.

Holmes EA, Brewin CR, Hennessy RG. Trauma films, information processing, and intrusive memory development. J Exp Psychol Gen. 2004;133:3-22.

Ehring T, Szeimies AK, Schaffrick C. An experimental analogue study into the role of abstract thinking in trauma-related rumination. Behav Res Ther. 2009;47:285-93.

Bourne C, Frasquilho F, Roth AD, Holmes EA. Is it mere distraction Peri-traumatic verbal tasks can increase analogue flashbacks but reduce voluntary memory performance. J Behav Ther Exp Psychiatry. 2010;41:316-24.

Holmes EA, Bourne C. Inducing and modulating intrusive emotional memories a review of the trauma film paradigm. Acta Psychol (Amst). 2008;127:553-66.

McNally RJ. Progress and controversy in the study of posttraumatic stress disorder. Annu Rev Psychol. 2003;54:229-52.

Ehlers A, Clark DM, Hackmann A, Grey N, Liness S, Wild J. Intensive cognitive therapy for PTSD a feasibility study. Behav Cogn Psychother. 2010;38:383-98.

Brewin CR. Autobiographical memory for trauma update on four controversies. Memory. 2007;15:227-48.

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